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Dec 09,  · Lipstick – One of the things that will help your lipstick look flawless is to use a lip brush to apply the lipstick instead of using it directly from the tube. Dip the lip brush into the lipstick and pack the colour onto the lips. Once you fill in the entire lip, go ahead and apply a second coat of colour. Feb 19,  · How to Make Lipstick Last today's video is about How to make your lipstick last longer. the video will focus on a few makeup tips and tricks on how to make y. You can get the same effects with a lip primer – simply apply a light coat of either primer or foundation and let it dry. Add your lipstick after that. You’ll be amazed at just how long it stays put. Don’t forget the lip pencil. So many of us skip this step, merely applying lip color directly to the lips without any sort of Azhearted Reading Time: 3 mins. Read more

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What this means is that drugs absorbed from the intestinal tract are taken straight to the liver before they can be distributed to the site of action. This is known as the first-pass effect or first-pass metabolism, where some of the drug is immediately metabolized in the liver before reaching systemic circulation. This reduces the bioavailability of orally administered drugs. FIRST PASS METABOLISM/ FIRSTPASS EFFECTS/ PRESYSTEMIC METABOLISM. It is the phenomenon of drug metabolism. Where the concentration of a drug is greatly reduced before it reaches the systemic circulation. Dose Destroyed in gut Not absorbed Destroyed by gut wall Destroyed by liver to systemic Azhear Size: KB. First-pass effect or also known as first-pass metabolism or presystemic metabolism is when an administered drug enters the liver and undergoes extensive biotransformation and thus decreasing the concentration rapidly before it reaches its target. Read more

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